Why We Love It: Known as Trichosanthes Kirilowii Root extract, this ingredient normalizes and improves skin's circadian rhythm, activates repair activity, inhibits cell senescence, and inhibits MMP 2,13 expression for an anti-wrinkle effect. Do you know what senescence means? Cellular senescence is a naturally-occurring process which is when cells halt their division. This happens as we age, which results in our skin looking less radiant and more dull. By blocking this process, we are extending the life of our skin cells.